Mitchell Holland - When Technicals Become Fundamentals (Total size: 111.6 MB Contains: 5 files)

Education

1. Postdoctoral Fellow, The Johns Hopkins University School of Medicine, Department of Pediatrics, Baltimore, Maryland. 1990
2. Ph.D. in Biochemistry, The University of Maryland, College Park, Maryland. 1989
3. Mentor: John A. Gerlt, Currently a Professor of Biochemistry, Gutgsell Chair, Professor of Chemistry, and Professor of Biophysics and Computational Biology, School of Molecular and Cellular Biology, University of Illinois.
4. B.S. in Chemistry, Hobart College, Geneva, New York. 1984

Biography

Dr. Holland holds a Bachelor of Science in Chemistry with a minor in Philosophy from Hobart Collage in Geneva, New York (1984). He earned his Ph.D. in Biochemistry at the University of Maryland College Park (1989) and was a Postdoctoral Fellow at the Johns Hopkins University School of Medicine in Baltimore, Maryland where he studied Human Genetics (1990).

Dr. Holland is a Fellow in the American Academy of Forensic Sciences, has served as an associate professorial lecturer in the Forensic Science Department at the George Washington University, and has been an adjunct faculty member at other colleges and universities. Dr. Holland has been on the Editorial Board of the Journal of Forensic Sciences and a member of the Advisory Board of the International Journal of Legal Medicine. He has held positions on governmental and company advisory boards (e.g., DMORT and Identigene Inc), and has been recognized by organizations for his work (e.g., by the FBI and NY City OCME).

Prior to being asked to help develop the Forensic Science program at Penn State, Dr. Holland was the Senior Vice President, Operations and Laboratory Director of The Bode Technology Group (Bode). Bode is one of the largest forensic DNA laboratories in the U.S., providing DNA identification services to public agencies and private citizens. Bode specializes in forensic casework, convicted offender databanking, forensic research, and product development. Dr. Holland oversaw the laboratory activities at Bode, as well as the IT, applied research, and wet-lab product development groups. Dr. Holland's laboratory at Bode was capable of producing greater than 30,000 forensic DNA profiles each month from sources such as convicted offender samples and victim family references. In addition, Dr. Holland's laboratory was capable of completing work on more than 800 forensic cases per month. Journal articles published by Dr. Holland while at Bode include;

• Development of a quality, high throughput DNA analysis procedure for skeletal samples to assist with the identification of victims from the world trade center attacks, MM Holland, CA Cave, CA Holland, TW Bille (2003) Croatian Medical Journal, 44(3), pp. 264-72
   
• Human hair histogenesis for the mitochondrial DNA forensic scientist, CA Linch, DA Whiting, MM Holland (2001) The Journal of Forensic Sciences, 46(4), pp. 844-53

From 1991-2000, Dr. Holland held various positions at the Armed Forces DNA Identification Laboratory (AFDIL) in Rockville, Md., including Scientific Laboratory Director from 1993-2000. At AFDIL, Dr. Holland was responsible for the laboratory that identified the remains of 1st Lt Michael Blassie (the Vietnam Unknown Soldier) and Tsar Nicholas Romanov. The focus of the work at AFDIL was the identification of U.S. military personnel killed in Vietnam, Korea, and as a result of conflicts during World War II. AFDIL continues to be responsible for the DNA identification of every U.S. military soldier killed while serving his/her country today. Journal articles published by Dr. Holland while at AFDIL include;

• A sensitive denaturing gradient-gel electrophoresis assay reveals a high frequency of heteroplasmy in hypervariable region I of the human mtDNA control region, LA Tully, TJ Parsons, RJ Steighner, MM Holland, MA Marino, VL Prenger (2000) American Journal of Human Genetics, 67(2), pp. 432-43
   
• Mitochondrial DNA sequence analysis validation and use for forensic casework, MM Holland, TJ Parsons (1999) Forensic Science Review, 11, pp. 21-50
   
• Amplification and sequencing of Mitochondrial DNA in forensic casework, RJ Steighner and MM Holland (1998) Methods in Molecular Biology: Forensic DNA Profiling Protocols, 98, pp. 213-224
   
• A high observed substitution rate in the human mitochondrial DNA control region, TJ Parsons, DS Muniec, K Sullivan, N Woodyatt, R Alliston-Greiner, MR Wilson, DL Berry, KA Holland, VW Weedn, P Gill, and MM Holland (1997) Nature Genetics, 15, pp. 363-368
   
• Mitochondrial DNA sequence heteroplasmy in the Grand Duke of Russia Georgij Romanov establishes the authenticity of the remains of Tsar Nicholas II, PL Ivanov, MJ Wadhams, RK Roby, MM Holland, VW Weedn, and TJ Parsons (1996) Nature Genetics, 12, pp. 417-420
   
• Establishing the identity of Anna Anderson Manahan, M Stoneking, T Melton, J Nott, S Barritt, R Roby, M Holland, V Weedn, P Gill, C Kimpton, R Aliston-Greiner, and K Sullivan (1995) Nature Genetics, 9(1), pp. 9-10

Dr. Holland has had extensive experience over the last 18 years with human remains identification cases, including the identification of victims from the World Trade Center disasters and from numerous commercial airline accidents.

Dr. Holland has given hundreds of lectures and/or presentations on forensic DNA analysis (many at professional conferences and seminars), and has published 40 peer reviewed journal articles, book chapters and other manuscripts. In addition, Dr. Holland has been qualified in numerous courts of law as an expert in forensic DNA analysis. Finally, Dr. Holland has established a consulting firm (www.forensicdnaconsultants.com ) to support the legal, law enforcement and crime laboratory communities.

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Mitchell Holland - When Technicals Become Fundamentals (Total size: 111.6 MB Contains: 5 files)

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